Research Fellow - Department of Cardiovascular Sciences - 108034 - Grade 7

This fixed-term position focuses on defining the mechanisms of vasculogenic mimicry in pediatric sarcomas and developing targeted therapies. Key responsibilities include designing and performing experiments, analyzing data, and contributing to grant writing. Essential requirements are a PhD, expertise in tumor microenvironment modeling, cell culture, microscopy, and transcriptional profiling, along with the ability to develop new methodologies.

• Develop research objectives and proposals for own or joint research, with assistance of a mentor if required
• Contribute to writing bids for research funding
• Apply knowledge in a way which develops new intellectual understanding
• Disseminate research findings for publication, research seminars etc
• Contribute to developing new models, techniques and methods
• Undertake management/administration arising from research
• Contribute to enterprise, business development and/or public engagement activities of manifest benefit to the College and the University, often under supervision of a project leader
• this may be through a variety of research methods, such as scientific experimentation, literature reviews, and research interviews
• Present research outputs, including drafting academic publications or parts thereof, for example at seminars and as posters
• Deal with problems that may affect the achievement of research objectives and deadlines
• Fosters a fair and equitable workplace for all staff
• Identify and respond to equality and diversity issues in line with relevant university policies and procedures
• Supervise students on research related work and provide guidance to PhD students where appropriate to the discipline
• Contribute to Departmental/School research-related activities and research-related administration
• Provide guidance, as required, to support staff and any students who may be assisting with the research
• Bring the ability to invent new, or adapt existing, methodologies.
• Analyse and interpret data, recommend next steps within the context of current literature.
• Keep accurate, comprehensive and clear records.

• High level analytical capability
• Ability to communicate complex information clearly
• Fluency in relevant models, techniques or methods and ability to contribute to developing new ones
• Ability to assess resource requirements and use resources effectively.
• Understanding of and ability to contribute to broader management/administration processes
• Co-ordinate own work with others to avoid conflict or duplication of effort
• Knowledge of the protected characteristics and duties under the Equality Act 2010. Including fostering good relations and advancing the universities Public Sector Equality Duty (PSED).
• Use of AI in applications: We want to understand your genuine interest in the role and for the written elements of your application to accurately reflect your own communication style.
• Applications that rely too heavily on AI tools can appear generic and lack the detail we need to assess your skills and experience.
• Such applications will unlikely be progressed to interview.
• Further particulars can be found here
• Further particulars can be found
• Essential: A PhD relevant to the research area (or near completion), or equivalent PhD level qualifications.
• Essential: Demonstrable research experience, or detailed knowledge of, tumour microenvironment modelling, particularly relating to tumour vasculature.
• Essential: Proficient skills in cell culture, 3D and co-culture assays, confocal microscopy and transcriptional profiling.
• Essential: Evidence of having developed or invented new methods and the ability to learn new approaches outside of current expertise.
• Desirable: Completion of PIL-A/B training by the Home Office and experience of in vivo modelling in zebrafish and/or mice.
• Desirable: Previous publication(s) as first author, presentations (talks or posters) at national or international conferences.
• Ability to contribute to the planning and organising of the research programme and/or specific research project
• Informal enquiries to Joseph Wragg, email: j.wragg@bham.ac.uk